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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | OAVG | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Satchel Paige# | .1641 | 1933-1940 | |
| 2 | Sherry Smith | .1700 | 1911-1927 | |
| 3 | Bob Shawkey | .1756 | 1913-1928 | |
| 4 | Babe Ruth | .1810 | 1914-1937 | |
| 5 | Lady Baldwin | .1818 | 1884-1890 | |
| 6 | Eddie Plank* | .1859 | 1901-1917 | |
| 7 | Lefty Tyler | .1864 | 1910-1924 | |
| 8 | Stan Coveleski | .1871 | 1912-1927 | |
| 9 | Willie Foster | .1901 | 1931-1939 | |
| 10 | Jimmy Ring | .1913 | 1917-1930 | |
| 11 | Ernie Shore | .1935 | 1912-1920 | |
| 12 | Tim Keefe | .1974 | 1880-1893 | |
| 13 | Orval Overall | .1979 | 1905-1913 | |
| 14 | Christy Mathewson* | .1989 | 1900-1916 | |
| 15 | Ed Reulbach | .2034 | 1905-1917 | |
| 16 | Deacon Phillippe | .2041 | 1899-1911 | |
| 17 | Mort Cooper# | .2051 | 1938-1941 | |
| 18 | George Mullin | .2074 | 1902-1915 | |
| 19 | Ed Crane | .2105 | 1884-1893 | |
| 20 | Chief Bender* | .2110 | 1903-1917 | |
| 21 | Jack Coombs | .2199 | 1906-1920 | |
| 22 | Bill Donovan | .2240 | 1898-1918 | |
| 23 | Mordecai Brown* | .2252 | 1903-1916 | |
| 23 | Eppa Rixey* | .2252 | 1912-1935 | |
| 25 | Rube Marquard* | .2301 | 1908-1924 | |
| 26 | Bill Dinneen | .2302 | 1898-1909 | |
| 27 | Jim McCormick | .2326 | 1878-1887 | |
| 28 | Cy Young* | .2336 | 1890-1911 | |
| 29 | Bob Caruthers | .2344 | 1884-1892 | |
| 30 | Jesse Haines | .2345 | 1918-1936 | |
| 31 | Roy Parmelee# | .2373 | 1930-1940 | |
| 32 | Pete Conway | .2385 | 1885-1889 | |
| 33 | Jeff Tesreau | .2400 | 1912-1918 | |
| 34 | Silver King | .2414 | 1886-1897 | |
| 35 | Eddie Cicotte* | .2428 | 1905-1920 | |
| 36 | Lefty Grove# | .2436 | 1925-1941 | |
| 37 | Carl Hubbell# | .2440 | 1928-1941 | |
| 38 | Jack Quinn | .2449 | 1909-1928 | |
| 39 | Tom Lovett | .2450 | 1885-1894 | |
| 40 | Red Faber* | .2451 | 1914-1931 | |
| 41 | Dutch Leonard | .2468 | 1913-1927 | |
| 42 | Rube Walberg | .2472 | 1923-1936 | |
| 43 | John Clarkson | .2500 | 1882-1894 | |
| 44 | Pretzels Getzien | .2596 | 1884-1892 | |
| 45 | Bobo Newsom# | .2628 | 1929-1941 | |
| 46 | Bill Hallahan | .2644 | 1926-1938 | |
| 47 | Bill Lohrman# | .2660 | 1935-1941 | |
| 48 | Dave Foutz | .2788 | 1884-1896 | |
| 49 | Ted Lyons# | .2791 | 1923-1941 | |
| 49 | Adonis Terry | .2791 | 1884-1897 | |
| 51 | Ice Box Chamberlin | .2826 | 1886-1896 | |
| 52 | Jack Pfiester | .2836 | 1903-1911 | |
| 53 | Sad Sam Jones | .2842 | 1914-1936 | |
| 54 | Dizzy Dean# | .2897 | 1930-1941 | |
| 55 | George Earnshaw | .2908 | 1928-1937 | |
| 56 | Waite Hoyt | .2919 | 1918-1940 | |
| 57 | Bill Walker# | .2938 | 1927-1938 | |
| 58 | Art Nehf | .3037 | 1915-1930 | |
| 59 | Paul Derringer# | .3125 | 1931-1941 | |
| 60 | Burleigh Grimes | .3386 | 1916-1932 | |
| 61 | Ted Trent | .3405 | 1937-1939 | |
| 62 | Hal Schumacher# | .3408 | 1931-1941 |
