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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Cy Young* | 7354.0 | 1890-1911 | |
| 2 | Walter Johnson* | 6653.0 | 1907-1930 | |
| 3 | Pud Galvin | 6003.0 | 1875-1892 | |
| 4 | Eppa Rixey* | 5351.0 | 1912-1935 | |
| 5 | Waite Hoyt | 5149.0 | 1918-1940 | |
| 6 | Kid Nichols* | 5056.0 | 1890-1906 | |
| 7 | Tim Keefe | 5047.0 | 1880-1893 | |
| 8 | Bobby Mathews | 4956.0 | 1871-1887 | |
| 9 | Mickey Welch | 4802.0 | 1880-1892 | |
| 10 | Christy Mathewson* | 4780.0 | 1900-1916 | |
| 11 | Herb Pennock | 4669.0 | 1912-1934 | |
| 12 | Lefty Grove# | 4562.0 | 1925-1941 | |
| 13 | John Clarkson | 4536.0 | 1882-1894 | |
| 14 | Old Hoss Radbourn | 4535.0 | 1881-1891 | |
| 15 | Tony Mullane | 4531.0 | 1881-1894 | |
| 16 | Eddie Plank* | 4495.0 | 1901-1917 | |
| 17 | Jack J Powell | 4389.0 | 1897-1912 | |
| 18 | Gus Weyhing | 4324.0 | 1887-1901 | |
| 19 | Jim McCormick | 4275.0 | 1878-1887 | |
| 20 | Red Ruffing# | 4189.0 | 1924-1941 | |
| 21 | George Uhle | 4141.0 | 1919-1936 | |
| 22 | Dazzy Vance | 4125.0 | 1915-1937 | |
| 23 | Red Faber* | 4046.0 | 1914-1931 | |
| 24 | Sad Sam Jones | 4013.0 | 1914-1936 | |
| 25 | Carl Hubbell# | 3999.0 | 1928-1941 | |
| 26 | Vic Willis | 3996.0 | 1898-1910 | |
| 27 | Pete Alexander* | 3837.0 | 1911-1929 | |
| 28 | Earl Whitehill | 3835.0 | 1923-1940 | |
| 29 | Amos Rusie | 3769.0 | 1889-1901 | |
| 30 | Burleigh Grimes | 3749.0 | 1916-1932 | |
| 31 | George Mullin | 3686.0 | 1902-1915 | |
| 32 | Charlie Root# | 3655.0 | 1923-1941 | |
| 33 | Jesse Haines | 3635.0 | 1918-1936 | |
| 34 | Tommy Bond | 3628.0 | 1874-1884 | |
| 35 | Bill Doak | 3610.0 | 1912-1929 | |
| 36 | Bill Sherdel | 3551.0 | 1918-1932 | |
| 37 | Will White | 3542.0 | 1877-1886 | |
| 38 | Adonis Terry | 3514.0 | 1884-1897 | |
| 39 | Lee Meadows | 3504.0 | 1915-1929 | |
| 40 | Jim Whitney | 3496.0 | 1881-1890 | |
| 41 | Freddie Fitzsimmons# | 3456.0 | 1925-1941 | |
| 42 | Joe McGinnity | 3441.0 | 1899-1908 | |
| 43 | Charlie Buffinton | 3404.0 | 1882-1892 | |
| 44 | Hippo Vaughn* | 3394.0 | 1908-1925 | |
| 45 | Clark Griffith | 3385.0 | 1891-1914 | |
| 46 | Jimmy Ring | 3379.0 | 1917-1930 | |
| 47 | Ted Lyons# | 3365.0 | 1923-1941 | |
| 48 | Chick Fraser | 3356.0 | 1896-1909 | |
| 49 | Al Orth | 3354.0 | 1895-1909 | |
| 50 | Jack Quinn | 3318.0 | 1909-1928 | |
| 51 | Bob Shawkey | 3275.0 | 1913-1928 | |
| 52 | Rube Walberg | 3274.0 | 1923-1936 | |
| 53 | Howard Ehmke | 3268.0 | 1915-1932 | |
| 54 | Tom Zachary | 3238.0 | 1918-1938 | |
| 55 | Eddie Cicotte* | 3223.0 | 1905-1920 | |
| 55 | Art Nehf | 3223.0 | 1915-1930 | |
| 57 | Red Ames | 3198.0 | 1903-1919 | |
| 58 | Silver King | 3190.0 | 1886-1897 | |
| 59 | Mordecai Brown* | 3172.0 | 1903-1916 | |
| 60 | Bill Hutchinson | 3078.0 | 1884-1897 | |
| 61 | Bill Dinneen | 3074.0 | 1898-1909 | |
| 62 | Bullet Joe Bush | 3072.0 | 1912-1928 | |
| 63 | Doc White | 3041.0 | 1901-1913 | |
| 64 | Rube Marquard* | 3040.0 | 1908-1924 | |
| 65 | Brickyard Kennedy | 3021.0 | 1892-1903 | |
| 66 | Chief Bender* | 3016.0 | 1903-1917 | |
| 67 | Pink Hawley | 3012.0 | 1892-1901 | |
| 68 | Bill Hallahan | 2992.0 | 1926-1938 | |
| 69 | Wilbur Cooper | 2988.0 | 1912-1926 | |
| 70 | Dizzy Dean# | 2987.0 | 1930-1941 | |
| 71 | Slim Sallee | 2971.0 | 1908-1924 | |
| 72 | Danny MacFayden# | 2967.0 | 1926-1940 | |
| 73 | Red Donahue | 2966.0 | 1893-1906 | |
| 74 | Bill Donovan | 2964.0 | 1898-1918 | |
| 74 | Ted Breitenstein | 2964.0 | 1891-1901 | |
| 74 | Ed Walsh* | 2964.0 | 1904-1917 | |
| 77 | Rube Waddell* | 2961.0 | 1897-1910 | |
| 78 | Dolf Luque | 2944.0 | 1914-1934 | |
| 79 | Rube Benton | 2941.0 | 1910-1930 | |
| 80 | George Bradley | 2940.0 | 1875-1884 | |
| 81 | Guy Hecker | 2906.0 | 1882-1890 | |
| 82 | Bump Hadley | 2900.0 | 1926-1940 | |
| 83 | Jack Chesbro | 2896.0 | 1899-1909 | |
| 84 | Al Spalding | 2890.0 | 1871-1877 | |
| 85 | Jack Stivetts | 2887.0 | 1889-1899 | |
| 86 | Hooks Dauss | 2884.0 | 1912-1924 | |
| 87 | Babe Adams | 2875.0 | 1906-1927 | |
| 88 | Paul Derringer# | 2868.0 | 1931-1941 | |
| 89 | Lon Warneke# | 2847.0 | 1930-1941 | |
| 90 | Bob Caruthers | 2828.0 | 1884-1892 | |
| 91 | Mark Baldwin | 2811.0 | 1887-1893 | |
| 92 | Frank Dwyer | 2810.0 | 1888-1899 | |
| 93 | Vic Aldridge | 2787.0 | 1917-1930 | |
| 94 | Earl Moore | 2776.0 | 1901-1914 | |
| 95 | Rip Collins | 2771.0 | 1920-1933 | |
| 96 | Red Ehret | 2754.0 | 1888-1898 | |
| 97 | Jesse Tannehill | 2750.0 | 1894-1911 | |
| 98 | Van Mungo# | 2745.0 | 1931-1941 | |
| 99 | Bert Cunningham | 2726.0 | 1887-1901 | |
| 100 | Willis Hudlin# | 2722.0 | 1926-1941 |
