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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Satchel Paige# | 7.32 | 1928-1941 | |
| 2 | Luis Tiant# | 6.10 | 1933-1939 | |
| 3 | Dave Brown | 5.26 | 1921-1927 | |
| 4 | Lefty Gomez# | 5.09 | 1929-1941 | |
| 5 | Leon Day# | 5.05 | 1935-1941 | |
| 6 | Fay Thomas# | 4.93 | 1930-1940 | |
| 7 | Smokey Joe Williams | 4.90 | 1921-1923 | |
| 8 | Monte Pearson# | 4.83 | 1929-1941 | |
| 9 | Hilton Smith# | 4.78 | 1936-1941 | |
| 10 | Willie Foster | 4.77 | 1924-1938 | |
| 11 | Juan Padron | 4.67 | 1921-1925 | |
| 12 | Johnny Lindell# | 4.63 | 1938-1941 | |
| 13 | Lou Tost# | 4.59 | 1934-1941 | |
| 14 | Howard Craghead# | 4.49 | 1926-1941 | |
| 15 | Martín Dihigo# | 4.43 | 1924-1941 | |
| 16 | Bill Holland# | 4.36 | 1921-1936 | |
| 17 | Dick Redding | 4.32 | 1921-1928 | |
| 17 | Andy Porter# | 4.32 | 1934-1941 | |
| 19 | Bullet Rogan | 4.26 | 1921-1929 | |
| 20 | Nip Winters | 4.22 | 1922-1932 | |
| 21 | Luther Farrell | 4.17 | 1923-1936 | |
| 22 | John Donaldson | 4.15 | 1921-1926 | |
| 23 | Ted Trent | 4.12 | 1930-1937 | |
| 24 | Lefty Weinert | 4.07 | 1924-1933 | |
| 25 | Bill Posedel# | 3.86 | 1929-1940 | |
| 26 | Joe Bowman# | 3.85 | 1929-1933 | |
| 27 | Ralph Buxton# | 3.84 | 1934-1941 | |
| 28 | Ad Liska# | 3.83 | 1936-1941 | |
| 28 | Phil Page# | 3.83 | 1931-1941 | |
| 30 | Tony Freitas# | 3.79 | 1928-1941 | |
| 31 | Ray Prim# | 3.77 | 1936-1941 | |
| 32 | Win Ballou# | 3.74 | 1927-1941 | |
| 33 | George Britt | 3.71 | 1921-1934 | |
| 33 | Oscar Levis | 3.71 | 1922-1933 | |
| 35 | Ed Brandt | 3.65 | 1924-1940 | |
| 36 | Wayne Carr | 3.62 | 1921-1928 | |
| 37 | Sam Gibson# | 3.55 | 1931-1941 | |
| 38 | Dick Barrett# | 3.54 | 1935-1941 | |
| 39 | Bill Byrd# | 3.43 | 1934-1939 | |
| 40 | Duster Mails | 3.42 | 1922-1934 | |
| 41 | Joe A Berry# | 3.34 | 1936-1941 | |
| 42 | Gordon Maltzberger# | 3.29 | 1932-1941 | |
| 43 | Slim Love | 3.27 | 1921-1925 | |
| 44 | Glen Gabler# | 3.26 | 1927-1941 | |
| 45 | Ray Keating | 3.23 | 1925-1932 | |
| 46 | Dick Niehaus | 3.20 | 1921-1927 | |
| 47 | Script Lee | 3.18 | 1922-1935 | |
| 48 | Andy Cooper | 3.16 | 1921-1931 | |
| 49 | Larry French# | 3.12 | 1926-1941 | |
| 49 | Willie Mitchell | 3.12 | 1921-1926 | |
| 51 | Syl Johnson# | 3.11 | 1921-1941 | |
| 52 | Frank Shellenback | 2.97 | 1921-1939 | |
| 52 | Ray Brown# | 2.97 | 1933-1941 | |
| 52 | Hank McDonald | 2.97 | 1929-1939 | |
| 55 | Ken Douglas | 2.95 | 1921-1938 | |
| 56 | Lefty Vinci | 2.93 | 1924-1933 | |
| 57 | Otho Nitcholas# | 2.91 | 1934-1939 | |
| 58 | Roy Joiner# | 2.90 | 1926-1941 | |
| 59 | Dick Ward | 2.87 | 1932-1939 | |
| 60 | Wally Hebert# | 2.85 | 1934-1941 | |
| 60 | Dutch Lieber# | 2.85 | 1929-1941 | |
| 62 | Fred Hutchinson# | 2.82 | 1938-1941 | |
| 63 | Manny Salvo# | 2.73 | 1932-1938 | |
| 64 | Pete Daglia | 2.68 | 1925-1939 | |
| 65 | Ray Kremer | 2.67 | 1921-1934 | |
| 66 | Paul Gregory# | 2.65 | 1934-1941 | |
| 67 | Jack Salveson# | 2.62 | 1936-1941 | |
| 68 | Ed Baecht | 2.61 | 1927-1936 | |
| 69 | Elmer Jacobs | 2.60 | 1921-1931 | |
| 70 | Jim Turner# | 2.59 | 1930-1936 | |
| 70 | Walt Leverenz | 2.59 | 1921-1928 | |
| 72 | Willie Ludolph | 2.56 | 1921-1937 | |
| 73 | Darltie Cooper | 2.55 | 1928-1936 | |
| 74 | Leo Mangum | 2.54 | 1926-1933 | |
| 75 | Rudy Kallio | 2.52 | 1921-1933 | |
| 76 | George Darrow# | 2.50 | 1935-1941 | |
| 77 | Ken Penner | 2.48 | 1921-1932 | |
| 78 | Claude Thomas | 2.47 | 1921-1927 | |
| 79 | Bert Cole | 2.43 | 1922-1934 | |
| 80 | Herman Pillette# | 2.37 | 1921-1941 | |
| 81 | Vance Page# | 2.33 | 1930-1935 | |
| 82 | Bill Prough | 2.30 | 1921-1926 | |
| 83 | Hal Turpin# | 2.24 | 1927-1941 | |
| 84 | Don Osborn# | 2.22 | 1929-1941 | |
| 85 | Curt Davis# | 2.16 | 1929-1933 | |
| 86 | Syd Cohen# | 2.09 | 1932-1940 | |
| 87 | Paul Fittery | 1.99 | 1921-1926 | |
| 88 | Doc Crandall | 1.62 | 1921-1929 |
