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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Bill Holland# | 316 | 1921-1936 | |
| 2 | Nip Winters | 268 | 1922-1932 | |
| 3 | Andy Cooper | 236 | 1921-1931 | |
| 3 | Satchel Paige# | 236 | 1928-1941 | |
| 5 | Willie Ludolph | 221 | 1921-1937 | |
| 6 | Frank Shellenback | 197 | 1921-1939 | |
| 7 | Win Ballou# | 180 | 1927-1941 | |
| 8 | Luis Tiant# | 171 | 1933-1939 | |
| 9 | Wayne Carr | 161 | 1921-1928 | |
| 10 | Willie Foster | 157 | 1924-1938 | |
| 11 | Andy Porter# | 152 | 1934-1941 | |
| 12 | Luther Farrell | 150 | 1923-1936 | |
| 13 | Bill Byrd# | 144 | 1934-1939 | |
| 14 | Herman Pillette# | 143 | 1921-1941 | |
| 15 | Ken Douglas | 131 | 1921-1938 | |
| 16 | Tony Freitas# | 130 | 1928-1941 | |
| 17 | Elmer Jacobs | 129 | 1921-1931 | |
| 17 | Ted Trent | 129 | 1930-1937 | |
| 19 | Hal Turpin# | 122 | 1927-1941 | |
| 20 | Howard Craghead# | 120 | 1926-1941 | |
| 20 | Syl Johnson# | 120 | 1921-1941 | |
| 22 | Ken Penner | 116 | 1921-1932 | |
| 23 | Phil Page# | 115 | 1931-1941 | |
| 23 | Jim Turner# | 115 | 1930-1936 | |
| 25 | Curt Davis# | 111 | 1929-1933 | |
| 26 | Lou Tost# | 110 | 1934-1941 | |
| 27 | Lefty Gomez# | 109 | 1929-1941 | |
| 28 | Paul Gregory# | 107 | 1934-1941 | |
| 29 | Ad Liska# | 106 | 1936-1941 | |
| 30 | Leo Mangum | 105 | 1926-1933 | |
| 30 | Ollie Mitchell | 105 | 1922-1928 | |
| 32 | George Britt | 103 | 1921-1934 | |
| 32 | Darltie Cooper | 103 | 1928-1936 | |
| 34 | Vance Page# | 100 | 1930-1935 | |
| 35 | Dutch Lieber# | 99 | 1929-1941 | |
| 36 | Fay Thomas# | 98 | 1930-1940 | |
| 37 | Bill Posedel# | 97 | 1929-1940 | |
| 37 | Bullet Rogan | 97 | 1921-1929 | |
| 39 | Eustaquio Pedroso | 95 | 1921-1924 | |
| 40 | Rudy Kallio | 94 | 1921-1933 | |
| 40 | Ray Prim# | 94 | 1936-1941 | |
| 40 | Hilton Smith# | 94 | 1936-1941 | |
| 40 | Lefty Weinert | 94 | 1924-1933 | |
| 44 | Ed Brandt | 90 | 1924-1940 | |
| 44 | Doc Crandall | 90 | 1921-1929 | |
| 44 | Wally Hebert# | 90 | 1934-1941 | |
| 47 | Elmer Myers | 89 | 1922-1927 | |
| 48 | Pete Daglia | 88 | 1925-1939 | |
| 49 | Clyde Barfoot | 87 | 1924-1931 | |
| 49 | Ray Brown# | 87 | 1933-1941 | |
| 49 | Bill Prough | 87 | 1921-1926 | |
| 52 | John Singleton | 85 | 1923-1926 | |
| 53 | Leon Day# | 83 | 1935-1941 | |
| 54 | Bert Cole | 82 | 1922-1934 | |
| 55 | Jack Salveson# | 81 | 1936-1941 | |
| 56 | Julio Bonetti# | 80 | 1933-1941 | |
| 56 | Willie Gisentaner | 80 | 1924-1936 | |
| 56 | Roy Joiner# | 80 | 1926-1941 | |
| 56 | Hank McDonald | 80 | 1929-1939 | |
| 60 | George Caster# | 79 | 1929-1936 | |
| 60 | Duster Mails | 79 | 1922-1934 | |
| 62 | Martín Dihigo# | 78 | 1924-1941 | |
| 62 | Neck Stanley# | 78 | 1934-1941 | |
| 64 | Joe Bowman# | 77 | 1929-1933 | |
| 64 | Charlie Eckert | 77 | 1923-1928 | |
| 66 | Lloyd Johnson | 75 | 1930-1940 | |
| 67 | Ray Keating | 74 | 1925-1932 | |
| 68 | Wayne Osborne# | 73 | 1931-1941 | |
| 69 | Lefty Vinci | 72 | 1924-1933 | |
| 70 | Ralph Buxton# | 71 | 1934-1941 | |
| 70 | Oscar Levis | 71 | 1922-1933 | |
| 72 | Robert Poindexter | 70 | 1926-1931 | |
| 73 | Eddie Bryan | 69 | 1924-1933 | |
| 74 | Dave Brown | 67 | 1921-1927 | |
| 75 | Joe A Berry# | 65 | 1936-1941 | |
| 75 | Larry French# | 65 | 1926-1941 | |
| 75 | Dick McCabe | 65 | 1922-1929 | |
| 75 | George Payne | 65 | 1924-1927 | |
| 75 | William Ross | 65 | 1921-1927 | |
| 80 | Glen Gabler# | 64 | 1927-1941 | |
| 80 | Clarence Mitchell | 64 | 1929-1933 | |
| 82 | Harry Krause | 63 | 1921-1927 | |
| 82 | Sloppy Thurston | 63 | 1921-1936 | |
| 84 | Ed Baecht | 62 | 1927-1936 | |
| 84 | Rasty Wright | 62 | 1925-1929 | |
| 86 | Gordon Maltzberger# | 61 | 1932-1941 | |
| 87 | Harry Salmon | 60 | 1926-1929 | |
| 88 | Harry Kincannon# | 59 | 1936-1939 | |
| 88 | Sam Thompson# | 59 | 1935-1941 | |
| 90 | Syd Cohen# | 58 | 1932-1940 | |
| 90 | George Darrow# | 58 | 1935-1941 | |
| 90 | Willie Mitchell | 58 | 1921-1926 | |
| 90 | Otho Nitcholas# | 58 | 1934-1939 | |
| 94 | Johnny Miljus | 57 | 1925-1933 | |
| 95 | George Blaeholder | 56 | 1928-1939 | |
| 96 | Walt Leverenz | 55 | 1921-1928 | |
| 97 | Ray Kremer | 54 | 1921-1934 | |
| 97 | Script Lee | 54 | 1922-1935 | |
| 97 | Bud Teachout | 54 | 1927-1930 | |
| 100 | William Bell | 53 | 1926-1927 |
