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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Lou Gehrig# | 612 | 1923-1941 | |
| 2 | Jimmie Foxx# | 564 | 1925-1941 | |
| 3 | Hal Trosky Sr# | 270 | 1933-1941 | |
| 4 | Jim Bottomley | 225 | 1922-1939 | |
| 5 | Johnny Mize# | 214 | 1936-1941 | |
| 6 | Hank Greenberg# | 211 | 1931-1941 | |
| 7 | Ripper Collins# | 205 | 1931-1941 | |
| 8 | Bill Terry | 178 | 1923-1938 | |
| 9 | Babe Herman# | 151 | 1926-1938 | |
| 10 | Joe Hauser | 150 | 1922-1930 | |
| 11 | Don Hurst | 141 | 1928-1938 | |
| 12 | Dolph Camilli# | 131 | 1931-1941 | |
| 12 | Roger Connor | 131 | 1880-1897 | |
| 14 | Zeke Bonura# | 130 | 1934-1941 | |
| 15 | Mule Suttles# | 121 | 1933-1941 | |
| 16 | Joe Kuhel# | 114 | 1930-1941 | |
| 17 | George Sisler* | 103 | 1915-1931 | |
| 18 | Dan Brouthers | 98 | 1879-1904 | |
| 19 | Cap Anson | 95 | 1871-1897 | |
| 20 | Joe Judge | 88 | 1915-1932 | |
| 21 | Jake Beckley | 86 | 1888-1907 | |
| 21 | Phil Todt | 86 | 1924-1937 | |
| 23 | Fred Luderus | 84 | 1909-1920 | |
| 24 | Del Bissonette | 83 | 1928-1935 | |
| 25 | Wally Pipp | 75 | 1913-1930 | |
| 25 | Gus Suhr# | 75 | 1929-1941 | |
| 27 | Harry H Davis | 73 | 1895-1917 | |
| 28 | Ed Konetchy | 71 | 1907-1924 | |
| 29 | Dale Alexander | 70 | 1929-1937 | |
| 30 | John Reilly | 69 | 1880-1891 | |
| 31 | George H Burns | 68 | 1914-1935 | |
| 32 | Fred Merkle | 61 | 1907-1920 | |
| 33 | Hal Chase | 57 | 1905-1919 | |
| 34 | Jack Fournier | 55 | 1912-1922 | |
| 34 | Vic Saier | 55 | 1911-1919 | |
| 36 | Jake Daubert | 51 | 1910-1924 | |
| 36 | Harry Stovey | 51 | 1880-1893 | |
| 38 | Charlie Grimm | 50 | 1916-1937 | |
| 38 | Tommy Henrich# | 50 | 1937-1941 | |
| 40 | Earl Sheely | 49 | 1921-1932 | |
| 41 | Sam Leslie | 48 | 1929-1939 | |
| 42 | Ed Morgan | 46 | 1928-1936 | |
| 43 | Joe Harris | 44 | 1914-1932 | |
| 44 | Ted Strong# | 43 | 1939-1941 | |
| 45 | Ray Grimes | 42 | 1920-1927 | |
| 45 | Tommy Tucker | 42 | 1887-1899 | |
| 47 | Dan McGann | 40 | 1896-1908 | |
| 48 | Candy LaChance | 39 | 1893-1905 | |
| 49 | Elbie Fletcher# | 37 | 1934-1941 | |
| 49 | Henry Larkin | 37 | 1884-1893 | |
| 49 | Dave Orr | 37 | 1883-1890 | |
| 52 | George Grantham | 36 | 1922-1936 | |
| 52 | John Morrill | 36 | 1876-1890 | |
| 54 | Lu Blue | 34 | 1921-1932 | |
| 55 | Jud Wilson# | 33 | 1933-1941 | |
| 56 | Frank McCormick# | 32 | 1934-1941 | |
| 56 | Billy O'Brien | 32 | 1884-1890 | |
| 58 | Chicken Hawks | 31 | 1921-1929 | |
| 58 | Tim Jordan | 31 | 1901-1910 | |
| 60 | George Kelly | 30 | 1915-1932 | |
| 61 | Charlie Comiskey | 29 | 1882-1894 | |
| 61 | Jake Stahl | 29 | 1903-1913 | |
| 63 | George McQuinn# | 28 | 1936-1941 | |
| 64 | Dick Hoblitzell | 27 | 1908-1918 | |
| 65 | Bunny Brief | 26 | 1912-1924 | |
| 65 | Perry Werden | 26 | 1884-1897 | |
| 67 | Cliff W Lee | 25 | 1919-1927 | |
| 67 | Phil Weintraub# | 25 | 1933-1940 | |
| 69 | Ed Cartwright | 24 | 1890-1897 | |
| 69 | Charlie Hickman | 24 | 1897-1908 | |
| 69 | Walter Holke | 24 | 1914-1927 | |
| 72 | Rube Bressler | 20 | 1914-1932 | |
| 72 | Mickey Heath | 20 | 1934-1938 | |
| 74 | Stuffy McInnis | 19 | 1909-1927 | |
| 74 | Dots Miller | 19 | 1909-1923 | |
| 76 | Frank Chance | 18 | 1898-1914 | |
| 76 | Sid Farrar | 18 | 1883-1890 | |
| 76 | John Ganzel | 18 | 1898-1908 | |
| 76 | Buck Jordan# | 18 | 1928-1941 | |
| 80 | Harry Heilmann | 17 | 1914-1920 | |
| 80 | Bill B Phillips | 17 | 1879-1888 | |
| 80 | Ray Schmandt | 17 | 1915-1925 | |
| 80 | Fred Tenney | 17 | 1894-1911 | |
| 84 | Fred Beck | 16 | 1909-1915 | |
| 84 | Mike Grady | 16 | 1894-1906 | |
| 86 | John J Anderson | 15 | 1894-1908 | |
| 86 | Jack Doyle | 15 | 1889-1905 | |
| 86 | Buck J Freeman | 15 | 1891-1907 | |
| 86 | Nap Lajoie* | 15 | 1896-1916 | |
| 86 | Art Shires | 15 | 1928-1935 | |
| 86 | Joe Start | 15 | 1871-1886 | |
| 86 | George Stovall | 15 | 1904-1915 | |
| 93 | Buck Ewing | 14 | 1880-1897 | |
| 93 | John Kerins | 14 | 1884-1890 | |
| 93 | Alex McKinnon | 14 | 1884-1887 | |
| 93 | Max E West# | 14 | 1935-1941 | |
| 97 | Kitty Bransfield | 13 | 1898-1911 | |
| 97 | Phil Cavarretta# | 13 | 1934-1941 | |
| 97 | John Fenton | 13 | 1930-1932 | |
| 97 | Dave Foutz | 13 | 1884-1896 |
