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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Turkey Stearnes# | 591 | 1921-1941 | |
| 2 | Wally Berger# | 541 | 1927-1941 | |
| 3 | Tony Lazzeri# | 432 | 1922-1941 | |
| 4 | George Scales# | 343 | 1922-1941 | |
| 5 | Earl Averill# | 337 | 1926-1941 | |
| 6 | Bob Johnson# | 295 | 1929-1941 | |
| 7 | Gene Lillard# | 285 | 1932-1941 | |
| 8 | Martín Dihigo# | 284 | 1924-1941 | |
| 9 | Oscar Charleston# | 272 | 1921-1936 | |
| 10 | John Beckwith* | 271 | 1921-1935 | |
| 11 | Willie Wells# | 269 | 1925-1941 | |
| 12 | Buzz Arlett | 245 | 1921-1937 | |
| 13 | Josh Gibson# | 234 | 1931-1941 | |
| 14 | Ray Jacobs | 225 | 1923-1938 | |
| 15 | Biz Mackey# | 202 | 1921-1939 | |
| 16 | Johnny Frederick# | 179 | 1923-1941 | |
| 17 | Lefty O'Doul | 172 | 1921-1937 | |
| 18 | Vince DiMaggio# | 159 | 1932-1941 | |
| 19 | Chick Hafey | 157 | 1924-1938 | |
| 20 | Smead Jolley# | 151 | 1925-1941 | |
| 20 | Buck Leonard# | 151 | 1934-1941 | |
| 22 | Ike Boone | 147 | 1926-1932 | |
| 22 | Mule Suttles# | 147 | 1922-1930 | |
| 24 | Cristobal Torriente | 137 | 1921-1931 | |
| 25 | Ernie Lombardi# | 135 | 1927-1941 | |
| 26 | Joe DiMaggio# | 134 | 1932-1941 | |
| 27 | Heavy Johnson | 124 | 1921-1930 | |
| 28 | Joe Cronin# | 118 | 1926-1941 | |
| 29 | Mike Hunt# | 115 | 1930-1941 | |
| 30 | Irvin Hufft | 113 | 1926-1935 | |
| 31 | Fred Berger# | 108 | 1928-1938 | |
| 32 | Cool Papa Bell# | 106 | 1923-1938 | |
| 33 | Frank Brazill | 105 | 1922-1928 | |
| 34 | Jack Fournier | 99 | 1923-1928 | |
| 35 | Dutch Holland | 98 | 1930-1936 | |
| 36 | Freddie Muller# | 97 | 1928-1941 | |
| 37 | Leo Ostenberg | 96 | 1926-1935 | |
| 38 | Harry Heilmann | 95 | 1921-1931 | |
| 39 | Jeff Heath# | 90 | 1936-1941 | |
| 39 | Crush Holloway | 90 | 1921-1931 | |
| 41 | Bob Meusel | 89 | 1921-1928 | |
| 42 | Prince Oana# | 87 | 1929-1941 | |
| 43 | Ted Williams# | 84 | 1936-1941 | |
| 44 | George Quellich | 82 | 1923-1932 | |
| 44 | Jud Wilson# | 82 | 1923-1930 | |
| 46 | Jerry Donovan | 81 | 1926-1939 | |
| 47 | Rap Dixon | 77 | 1924-1935 | |
| 47 | Dobie Moore | 77 | 1921-1927 | |
| 47 | Charlie Smith | 77 | 1926-1930 | |
| 47 | Jigger Statz# | 77 | 1921-1941 | |
| 51 | George Grantham | 76 | 1921-1926 | |
| 52 | George H Burns | 75 | 1930-1934 | |
| 52 | Dolph Camilli# | 75 | 1926-1933 | |
| 52 | Orville Riggins | 75 | 1921-1929 | |
| 55 | Jim Oglesby | 73 | 1932-1937 | |
| 56 | Joe Gordon# | 72 | 1936-1941 | |
| 57 | George Kelly | 70 | 1921-1935 | |
| 58 | Max E West# | 64 | 1935-1937 | |
| 59 | Harry Green | 63 | 1928-1933 | |
| 60 | Ed Coleman# | 61 | 1929-1941 | |
| 60 | Duffy Lewis | 61 | 1921-1924 | |
| 62 | Dick Bartell# | 60 | 1930-1938 | |
| 62 | Dick Lundy | 60 | 1921-1933 | |
| 64 | Jesse Hill# | 59 | 1930-1934 | |
| 65 | Cleo Carlyle | 58 | 1928-1938 | |
| 66 | Larry Brown# | 57 | 1921-1941 | |
| 67 | Bobby Doerr# | 54 | 1934-1941 | |
| 68 | Monte Irvin# | 53 | 1939-1941 | |
| 68 | Lyn Lary# | 53 | 1925-1937 | |
| 70 | Don Hurst | 52 | 1936-1938 | |
| 71 | Newt Allen | 49 | 1923-1940 | |
| 71 | Buzz Clarkson# | 49 | 1939-1941 | |
| 73 | Walter Cannady# | 48 | 1923-1927 | |
| 73 | Frank Demaree# | 48 | 1930-1932 | |
| 73 | Wally Hood | 48 | 1922-1928 | |
| 76 | Jim Poole | 47 | 1921-1924 | |
| 77 | Carl Dittmar | 46 | 1927-1940 | |
| 77 | Art Garibaldi# | 46 | 1931-1941 | |
| 79 | Joe Manger | 45 | 1922-1930 | |
| 79 | Ray Rohwer | 45 | 1923-1929 | |
| 81 | Babe Herman# | 44 | 1925-1941 | |
| 81 | Bevo LeBourveau | 44 | 1924-1932 | |
| 81 | Les Sheehan | 44 | 1921-1928 | |
| 84 | Arky Vaughan# | 43 | 1932-1941 | |
| 85 | Mickey Heath | 42 | 1927-1934 | |
| 86 | Pinky Higgins# | 41 | 1931-1940 | |
| 86 | Myril Hoag# | 41 | 1926-1940 | |
| 86 | Red Kress# | 41 | 1930-1938 | |
| 89 | Mickey Cochrane | 40 | 1924-1935 | |
| 89 | George LaFayette | 40 | 1921-1927 | |
| 91 | Frankie Crosetti# | 39 | 1928-1934 | |
| 91 | Frank Sigafoos | 39 | 1927-1935 | |
| 93 | Jim Keesey | 38 | 1928-1933 | |
| 94 | Nick H Cullop | 37 | 1937-1940 | |
| 95 | Willard Brown# | 36 | 1936-1941 | |
| 95 | Ripper Collins# | 36 | 1938-1939 | |
| 95 | Art Koehler | 36 | 1921-1931 | |
| 98 | Lou Novikoff# | 35 | 1939-1940 | |
| 98 | Rip Russell# | 35 | 1936-1938 | |
| 100 | Frank Brower | 34 | 1925-1927 |
