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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Hack Wilson | 303 | 1923-1937 | |
| 2 | Cy Williams | 235 | 1912-1930 | |
| 3 | Hank Leiber# | 144 | 1933-1941 | |
| 4 | Bing Miller | 91 | 1921-1936 | |
| 5 | Tris Speaker* | 87 | 1907-1929 | |
| 6 | Ben Chapman# | 86 | 1930-1941 | |
| 7 | Jimmy Ryan | 85 | 1885-1903 | |
| 8 | Johnny Frederick# | 82 | 1929-1934 | |
| 9 | Sam West# | 79 | 1927-1941 | |
| 10 | Sam Chapman# | 75 | 1938-1941 | |
| 11 | Ty Cobb* | 66 | 1905-1929 | |
| 12 | Baby Doll Jacobson | 63 | 1915-1929 | |
| 13 | Edd Roush | 61 | 1913-1933 | |
| 14 | Harry Craft# | 59 | 1937-1941 | |
| 15 | Earle Combs | 56 | 1924-1937 | |
| 15 | Len Koenecke | 56 | 1932-1937 | |
| 17 | Jimmy Welsh | 53 | 1925-1936 | |
| 18 | Paul Hines | 50 | 1872-1891 | |
| 18 | Bug Holliday | 50 | 1885-1898 | |
| 20 | Frank Demaree# | 49 | 1931-1941 | |
| 20 | Larry Rosenthal# | 49 | 1936-1941 | |
| 22 | George Watkins | 48 | 1930-1938 | |
| 23 | Mule Haas | 45 | 1925-1938 | |
| 24 | Heinie C Mueller | 44 | 1920-1930 | |
| 25 | Ethan Allen | 42 | 1926-1939 | |
| 25 | Mike J Griffin | 42 | 1887-1898 | |
| 27 | Benny Kauff | 41 | 1912-1920 | |
| 27 | Terry Moore# | 41 | 1935-1941 | |
| 27 | Dode Paskert | 41 | 1907-1923 | |
| 27 | Fred Schulte | 41 | 1927-1939 | |
| 31 | Hugh Duffy | 40 | 1888-1906 | |
| 32 | Ginger Beaumont | 39 | 1899-1910 | |
| 32 | Max Carey | 39 | 1910-1927 | |
| 32 | George Van Haltren | 39 | 1887-1903 | |
| 35 | Happy Felsch | 38 | 1915-1920 | |
| 35 | Cy Seymour | 38 | 1896-1913 | |
| 37 | Tom T Brown | 37 | 1882-1898 | |
| 37 | Dummy Hoy | 37 | 1888-1902 | |
| 39 | George Gore | 34 | 1879-1892 | |
| 39 | Al Simmons# | 34 | 1924-1941 | |
| 41 | Ping Bodie | 33 | 1911-1921 | |
| 41 | Dick Johnston | 33 | 1884-1891 | |
| 41 | Hi Myers | 33 | 1909-1925 | |
| 44 | Mel Almada# | 32 | 1935-1941 | |
| 44 | Tommy Leach | 32 | 1898-1918 | |
| 46 | Mike Kreevich# | 31 | 1931-1941 | |
| 46 | Bill Lange | 31 | 1893-1899 | |
| 46 | Tillie Walker | 31 | 1911-1926 | |
| 49 | Billy Hamilton | 30 | 1888-1901 | |
| 49 | Ned Hanlon | 30 | 1880-1892 | |
| 49 | Dutch Zwilling | 30 | 1910-1916 | |
| 52 | Jake Stenzel | 28 | 1890-1899 | |
| 53 | Mike Donlin | 27 | 1899-1914 | |
| 54 | Harry Brown | 26 | 1923-1930 | |
| 54 | Pepper Martin# | 26 | 1928-1940 | |
| 54 | Pete Reiser# | 26 | 1940-1941 | |
| 54 | John Stone | 26 | 1928-1940 | |
| 58 | Fred Berger# | 25 | 1935-1941 | |
| 58 | Steve Brodie | 25 | 1890-1902 | |
| 58 | Ernie Orsatti | 25 | 1926-1936 | |
| 58 | Ray Powell | 25 | 1913-1925 | |
| 62 | Harry Rice | 24 | 1923-1936 | |
| 63 | Freddie Lindstrom | 23 | 1924-1937 | |
| 64 | Ira Flagstead | 22 | 1917-1930 | |
| 64 | Foy Frazier | 22 | 1928-1934 | |
| 64 | Hersh Martin# | 22 | 1937-1941 | |
| 64 | Bernie Neis | 22 | 1920-1930 | |
| 68 | Pete Browning | 21 | 1882-1894 | |
| 68 | Phil Cavarretta# | 21 | 1934-1941 | |
| 68 | Johnny Mostil | 21 | 1918-1929 | |
| 71 | Alex Metzler | 20 | 1925-1934 | |
| 72 | Pop Corkhill | 19 | 1883-1892 | |
| 72 | Charlie Duffee | 19 | 1889-1893 | |
| 72 | Bud Hafey# | 19 | 1935-1940 | |
| 72 | Charley Jones | 19 | 1875-1888 | |
| 72 | Clint Thomas | 19 | 1935-1939 | |
| 77 | Sam Crawford* | 18 | 1899-1917 | |
| 77 | Jim McTamany | 18 | 1885-1891 | |
| 77 | Lloyd Waner# | 18 | 1927-1941 | |
| 80 | Doc Cramer# | 17 | 1929-1941 | |
| 80 | Jim H O'Rourke | 17 | 1872-1904 | |
| 80 | Chick Stahl | 17 | 1897-1906 | |
| 80 | Curt Walker | 17 | 1919-1933 | |
| 84 | John J Anderson | 16 | 1894-1908 | |
| 84 | Johnny Bates | 16 | 1906-1914 | |
| 84 | Sam Mertes | 16 | 1896-1906 | |
| 84 | Jack Smith | 16 | 1915-1928 | |
| 84 | Curt Welch | 16 | 1884-1893 | |
| 89 | Charlie Abbey | 15 | 1893-1897 | |
| 89 | Jimmy Barrett | 15 | 1899-1908 | |
| 89 | Chet Laabs# | 15 | 1937-1941 | |
| 89 | Rebel Oakes | 15 | 1909-1915 | |
| 89 | Doc Smoot | 15 | 1902-1906 | |
| 94 | Emmet Heidrick | 14 | 1898-1908 | |
| 94 | Fielder Jones | 14 | 1896-1915 | |
| 94 | Ernie Koy# | 14 | 1938-1941 | |
| 94 | Jigger Statz# | 14 | 1919-1940 | |
| 94 | Chief Wilson | 14 | 1908-1916 | |
| 99 | Cool Papa Bell# | 13 | 1939-1941 | |
| 99 | Mandy Brooks | 13 | 1925-1931 |
