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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Willie Wells# | 269 | 1925-1941 | |
| 2 | Joe Cronin# | 115 | 1926-1941 | |
| 3 | Tony Lazzeri# | 89 | 1922-1941 | |
| 4 | Dobie Moore | 77 | 1921-1927 | |
| 5 | Orville Riggins | 75 | 1921-1929 | |
| 6 | Dick Bartell# | 60 | 1930-1938 | |
| 6 | Dick Lundy | 60 | 1921-1933 | |
| 8 | Carl Dittmar | 45 | 1927-1940 | |
| 9 | Lyn Lary# | 43 | 1925-1937 | |
| 10 | Monte Irvin# | 33 | 1939-1941 | |
| 11 | Arky Vaughan# | 29 | 1932-1941 | |
| 12 | Gordon Slade | 27 | 1923-1938 | |
| 12 | Jake Stephens | 27 | 1922-1935 | |
| 14 | Heinie Sand | 24 | 1921-1922 | |
| 15 | Buzz Clarkson# | 22 | 1939-1941 | |
| 16 | Frankie Crosetti# | 17 | 1928-1934 | |
| 17 | Bill Rodda | 14 | 1925-1931 | |
| 18 | Martín Dihigo# | 11 | 1924-1941 | |
| 18 | Eddie Joost# | 11 | 1933-1938 | |
| 18 | Vern Stephens# | 11 | 1941-1941 | |
| 21 | Freddie Muller# | 10 | 1928-1941 | |
| 22 | Ray Brubaker | 8 | 1921-1932 | |
| 22 | Walter Cannady# | 8 | 1923-1927 | |
| 24 | Bill Cissell | 7 | 1926-1939 | |
| 25 | Lonny Baker | 6 | 1926-1932 | |
| 25 | Sam Bankhead# | 6 | 1934-1941 | |
| 25 | Frank Emmer | 6 | 1924-1925 | |
| 25 | Ray French | 6 | 1921-1931 | |
| 25 | John Kerr | 6 | 1925-1928 | |
| 25 | Wes Kingdon | 6 | 1921-1927 | |
| 25 | Dud Lee | 6 | 1922-1933 | |
| 25 | Eddie Pellagrini# | 6 | 1941-1941 | |
| 25 | Frank Sigafoos | 6 | 1927-1935 | |
| 25 | Chester Williams# | 6 | 1934-1941 | |
| 35 | Bud Connolly | 5 | 1922-1928 | |
| 35 | Gil English# | 5 | 1934-1936 | |
| 35 | Rabbit Martinez# | 5 | 1936-1941 | |
| 38 | Bill Yancey | 4 | 1929-1932 | |
| 39 | Ike Caveney | 3 | 1921-1933 | |
| 39 | Wes Griffin | 3 | 1924-1934 | |
| 39 | John Henry Lloyd | 3 | 1921-1923 | |
| 42 | Clyde Beck | 2 | 1922-1935 | |
| 42 | Buddy Blattner# | 2 | 1940-1941 | |
| 42 | Pelayo Chacon | 2 | 1921-1929 | |
| 42 | Jim Cronin | 2 | 1927-1935 | |
| 42 | Nanny Fernandez# | 2 | 1940-1941 | |
| 42 | Dick Gyselman# | 2 | 1931-1941 | |
| 42 | Billy Orr | 2 | 1921-1923 | |
| 42 | Harvey Storey# | 2 | 1936-1941 | |
| 50 | Rabbit Benton | 1 | 1924-1925 | |
| 50 | Tommy Butts# | 1 | 1939-1941 | |
| 50 | Carl Cox# | 1 | 1939-1941 | |
| 50 | Chick Ellsworth | 1 | 1926-1937 | |
| 50 | Doc Farrell | 1 | 1931-1933 | |
| 50 | Eddie Lake# | 1 | 1939-1941 | |
| 50 | Jim Levey | 1 | 1934-1935 | |
| 50 | Doc E Marshall# | 1 | 1934-1941 | |
| 50 | Johnny Mitchell | 1 | 1926-1927 | |
| 50 | George Myatt# | 1 | 1934-1941 | |
| 50 | Hal Rhyne | 1 | 1922-1925 | |
| 50 | Alan Strange# | 1 | 1932-1939 | |
| 50 | Don Trower# | 1 | 1940-1940 | |
| 50 | Frank Warfield | 1 | 1921-1934 | |
| 50 | Chester Wilburn# | 1 | 1934-1939 | |
| 50 | Yats Wuestling | 1 | 1928-1930 | |
| 66 | Scotty Alcock | 0 | 1921-1921 | |
| 66 | Joe Berkowitz# | 0 | 1932-1940 | |
| 66 | Rainey Bibbs# | 0 | 1940-1940 | |
| 66 | Lindsay Brown# | 0 | 1940-1941 | |
| 66 | Percy Chavez | 0 | 1922-1923 | |
| 66 | Cuckoo Christensen | 0 | 1929-1934 | |
| 66 | Ed Cihocki# | 0 | 1938-1938 | |
| 66 | Stu Clarke | 0 | 1930-1930 | |
| 66 | Bernie DeViveiros | 0 | 1922-1936 | |
| 66 | Carter Elliott | 0 | 1921-1921 | |
| 66 | Charlie Gooch | 0 | 1925-1927 | |
| 66 | John Griffiths | 0 | 1938-1939 | |
| 66 | Joe Hewitt | 0 | 1922-1922 | |
| 66 | Joe Hoover# | 0 | 1938-1941 | |
| 66 | Bienvenido Jimenez | 0 | 1922-1925 | |
| 66 | Binky Jones | 0 | 1923-1923 | |
| 66 | Barney Kerns | 0 | 1921-1923 | |
| 66 | Wally Kimmick | 0 | 1921-1927 | |
| 66 | Eddie Leishman | 0 | 1931-1938 | |
| 66 | Bill Lillard# | 0 | 1937-1941 | |
| 66 | Bobby Mattick# | 0 | 1934-1936 | |
| 66 | Ike McAuley | 0 | 1921-1922 | |
| 66 | Patsy McGaffigan | 0 | 1921-1922 | |
| 66 | George McGinnis | 0 | 1923-1925 | |
| 66 | Herm Merritt | 0 | 1922-1922 | |
| 66 | Lenny Metz | 0 | 1926-1927 | |
| 66 | Harry Morse | 0 | 1921-1922 | |
| 66 | Eddie Mulligan | 0 | 1931-1933 | |
| 66 | Al Niemiec# | 0 | 1938-1940 | |
| 66 | Pat Patterson | 0 | 1921-1921 | |
| 66 | Walter Pearce | 0 | 1923-1925 | |
| 66 | Don Rader | 0 | 1923-1923 | |
| 66 | Buck Redfern | 0 | 1926-1929 | |
| 66 | Jimmie Reese | 0 | 1924-1940 | |
| 66 | Bill Rigney# | 0 | 1938-1941 |
